natashalopez010805 natashalopez010805 06-12-2021 Health contestada Which statement BEST describes antibiotic resistance? Antibiotic resistance occurs when the body builds up a resistance to antibiotics. Antibiotic resistance can occur when bacteria are exposed to an antibiotic. Antibiotic resistance occurs when antibiotics are not used. Antibiotic resistance is a big problem in the United States, but not the world.